Applied Chemistry, Vol. 2, Issue 1, Jun  2019, Pages 1-16; DOI: 10.31058/ 10.31058/

A Short Review on Antimicrobial Activity Study on Transition Metal Complexes of Ni Incorporating Schiff Bases

Applied Chemistry, Vol. 2, Issue 1, Jun  2019, Pages 1-16.

DOI: 10.31058/

Md. Saddam Hossain 1 , H. M. Tariqul Islam 1 , Md. Nuruzzaman Khan 1 , Abinash Chandro Sarker 1 , Bijan Mohon Chaki 1 , Abdul Latif 1 , Nasiruddin 2 , Ashraful Alam 3 , C.M. Zakaria 4 , Md. Kudrat-E-Zahan 4*

1 Department of Chemistry, Begum Rokeya University, Rangpur, Bangladesh

2 Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh

3 Department of Chemistry, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, Bangladesh

4 Department of Chemistry & Bioengineering, Faculty of Science and Engineering, Iwate University, Japan

Received: 6 December 2017; Accepted: 31 March 2019; Published: 5 June 2019

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Schiff bases and their complexes are flexible compounds synthesized from the condensation of an amino compound with carbonyl compounds and extensively used for industrial purposes and also show a broad range of biological activities including antibacterial, antifungal, antiviral, antimalarial, ant proliferative, anti-inflammatory, anticancer, anti-HIV, anthelminthic and antipyretic properties. Many Schiff base complexes show excellent catalytic activity in various reactions and in the presence of moisture. Over the past few years, there have been many reports on their applications in homogeneous and heterogeneous catalysis. The high thermal and moisture stabilities of many Schiff base complexes were useful attributes for their application as catalysts in reactions involving at high temperatures. The activity is usually increased by complexation therefore to understand the properties of both ligands and metal can lead to the synthesis of highly active compounds. The influence of certain metals on the biological activity of these compounds and their intrinsic chemical interest as multidentate ligands has prompted a considerable increase in the study of their coordination behavior. Development of a new chemotherapeutic Schiff bases and their metal complexes is now attracting the attention of medicinal chemists. This review compiles the antimicrobial activity of transition metal complexes of Ni over the few year decades.


Schiff Bases, Nickel Complexes, Antibacterial Activity, Antifungal Activity and Antiviral Activity


© 2017 by the authors. Licensee International Technology and Science Press Limited. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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