Health Research, Vol. 3, Issue 4, Dec  2019, Pages 1-14; DOI: 10.31058/j.hr.2019.34001 10.31058/j.hr.2019.34001

Rubella Seropositivity in Sudanese Children with Type I Diabetes Mellitus

, Vol. 3, Issue 4, Dec  2019, Pages 1-14.

DOI: 10.31058/j.hr.2019.34001

Hind TajAlser 1*

1 Department of Immunology, Sudan Academy of Science, Khartoum, Sudan

Received: 9 December 2019; Accepted: 9 December 2019; Published: 16 December 2019

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Abstract

Viruses have long been suspected to contribute to the onset of T1D; Rubella virus is a non-segmented,single-stranded RNA enveloped virus that belongs to the togavirus family. It has been implicated in T1D, as patients with congenital syndrome (CRS) had a higher incidence of T1D than the general population. It is objected that to evaluate the sero-prevalence of anti-rubella  IgG antibodies in type 1DM patients compared to non-diabetic  children.A total number of 45 diabetic type 1 patients and 45 as control were enrolled in the study.  Male to female ratio was 1: 1 among the  two groups. Age range  between 6 -18 years with a mean of 12,6  ±3.1   for the  patients and  the  range was 9 -18.   for the control  with a mean 16.5 ± 2.4 The majority of the participants were from Bahri locality.  All the participants declared  no history of rubella infection or vaccination against rubella taken  The result obtained in this study was that more than 75% of the study groups showed   IgG antibodies seropositivity   and insignificant correlation (p= 0.525) was found when comparing the diabetic patients with the control.

Keywords

Rubella Virus, Diabetes Mellitus (D.M), Children

Copyright

© 2017 by the authors. Licensee International Technology and Science Press Limited. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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